[{"@context":"http:\/\/schema.org\/","@type":"Article","@id":"https:\/\/sevgilibebek.com\/anne-karninda-kok-hucre-tedavisi-mumkun\/#Article","mainEntityOfPage":"https:\/\/sevgilibebek.com\/anne-karninda-kok-hucre-tedavisi-mumkun\/","headline":"Anne Karn\u0131nda K\u00f6k H\u00fccre Tedavisi M\u00fcmk\u00fcn","name":"Anne Karn\u0131nda K\u00f6k H\u00fccre Tedavisi M\u00fcmk\u00fcn","description":"Ana rahmindeki bebeklere\u00a0ileride olu\u015fabilecek hastal\u0131klar\u0131 \u00f6nlemek i\u00e7in\u00a0cenin k\u00f6k h\u00fccrelerinin enjekte edildi\u011fi ilk klinik denemenin yak\u0131nda ba\u015flayaca\u011f\u0131 a\u00e7\u0131kland\u0131. Ge\u00e7ti\u011fimiz Ocak ay\u0131 i\u00e7erisinde ba\u015flanan \u00e7al\u0131\u015fmada, \u0130sve\u00e7&#8217;teki Karolinska ve \u0130ngiltere&#8217;deki Great Ormond Street Hastanesi taraf\u0131ndan y\u00fcr\u00fct\u00fclecek ara\u015ft\u0131rmada kullan\u0131lacak<a class=\"moretag\" href=\"https:\/\/sevgilibebek.com\/anne-karninda-kok-hucre-tedavisi-mumkun\/\"> Devam\u0131n\u0131 oku&hellip;<\/a>","datePublished":"2022-03-31","dateModified":"2022-03-31","author":{"@type":"Person","@id":"https:\/\/sevgilibebek.com\/author\/3\/#Person","name":"Sevgili Bebek","url":"https:\/\/sevgilibebek.com\/author\/3\/","image":{"@type":"ImageObject","@id":"https:\/\/secure.gravatar.com\/avatar\/2916d3a243921c20e926d04a237431c8?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/2916d3a243921c20e926d04a237431c8?s=96&d=mm&r=g","height":96,"width":96}},"publisher":{"@type":"Organization","name":"Sevgili Bebek","logo":{"@type":"ImageObject","@id":"https:\/\/sevgilibebek.com\/wp-content\/uploads\/2017\/06\/cropped-sbikon.jpg","url":"https:\/\/sevgilibebek.com\/wp-content\/uploads\/2017\/06\/cropped-sbikon.jpg","width":600,"height":60}},"image":{"@type":"ImageObject","@id":"https:\/\/sevgilibebek.com\/wp-content\/uploads\/2017\/06\/anne-karninda-kok-hucre-tedavisi-mumkun.jpg","url":"https:\/\/sevgilibebek.com\/wp-content\/uploads\/2017\/06\/anne-karninda-kok-hucre-tedavisi-mumkun.jpg","height":450,"width":665},"url":"https:\/\/sevgilibebek.com\/anne-karninda-kok-hucre-tedavisi-mumkun\/","about":["Genel Sa\u011fl\u0131k"],"wordCount":631,"keywords":["anne karn\u0131nda k\u00f6k h\u00fccre tedavisi","anne karn\u0131nda tedavi","gebelik","gebelikte tedavi","k\u00f6k h\u00fccre tedavisi"],"articleBody":"Ana rahmindeki bebeklere\u00a0ileride olu\u015fabilecek hastal\u0131klar\u0131 \u00f6nlemek i\u00e7in\u00a0cenin k\u00f6k h\u00fccrelerinin enjekte edildi\u011fi ilk klinik denemenin yak\u0131nda ba\u015flayaca\u011f\u0131 a\u00e7\u0131kland\u0131.Ge\u00e7ti\u011fimiz Ocak ay\u0131 i\u00e7erisinde ba\u015flanan \u00e7al\u0131\u015fmada, \u0130sve\u00e7&#8217;teki Karolinska ve \u0130ngiltere&#8217;deki Great Ormond Street Hastanesi taraf\u0131ndan y\u00fcr\u00fct\u00fclecek ara\u015ft\u0131rmada kullan\u0131lacak k\u00f6k h\u00fccreler, k\u00fcrtajla sonland\u0131r\u0131lm\u0131\u015f gebeliklerden al\u0131narak, genetik olarak hastal\u0131k ihtimali bulunan ceninlere aktar\u0131lacak.Ara\u015ft\u0131rmada kullan\u0131lacak k\u00f6k h\u00fccrelerin bir dizi dokuyu d\u00f6n\u00fc\u015ft\u00fcr\u00fcp, ilk a\u015famada tedavisi olmayan cam kemik hastal\u0131\u011f\u0131n\u0131n belirtilerini hafifletmesi umuluyor.T\u0131ptaki ad\u0131 Osteogenesis imperfecta olan cam kemik hastal\u0131\u011f\u0131 her 25 bin do\u011fumdan birinde g\u00f6r\u00fcl\u00fcyor.Hastal\u0131k, bebe\u011fin kemiklerinde k\u0131r\u0131klarla do\u011fmas\u0131 halinde \u00f6l\u00fcmc\u00fcl olabiliyor. Hasta ya\u015fasa bile kemiklerde y\u0131lda 15 k\u0131r\u0131k, kolay k\u0131r\u0131lan di\u015fler, i\u015fitme bozuklu\u011fu ve b\u00fcy\u00fcme sorunlar\u0131yla kar\u015f\u0131la\u015f\u0131yor.Hastal\u0131k bebe\u011fin anne rahmindeki geli\u015fimi s\u0131ras\u0131nda DNA&#8217;s\u0131nda ortaya \u00e7\u0131kan hatadan kaynaklan\u0131yor. Bu ise kemikleri sa\u011flamla\u015ft\u0131ran kolajenin ya d\u00fc\u015f\u00fck kalitede olmas\u0131na ya da hi\u00e7 bulunmamas\u0131na yol a\u00e7\u0131yor.Yap\u0131lacak olan \u00e7al\u0131\u015fma ile, k\u00f6k h\u00fccrelerin kemik b\u00fcy\u00fcmesi s\u00fcrecindeki hatalar\u0131 gidermesi planlan\u0131yor.Great Ormond Street Hastanesi&#8217;nden Prof. Lyn Chitty, ara\u015ft\u0131rma kapsam\u0131nda testlerle hastal\u0131\u011fa yol a\u00e7an genetik hatalar\u0131 tespit edecek.Prof. Chitty &#8220;Bu \u00e7ok ciddi bir hastal\u0131k. Amac\u0131m\u0131z rahimdeki k\u00f6k h\u00fccre tedavisiyle hastal\u0131\u011f\u0131 hafifletmek ve k\u0131r\u0131k say\u0131s\u0131n\u0131 azaltmak&#8221; dedi.Rahimde ve do\u011fumdan sonra tedavi\u00c7al\u0131\u015fmada sa\u011fl\u0131kl\u0131 kemik, k\u0131k\u0131rdak ve kas dokusu geli\u015ftiren bir t\u00fcr k\u00f6k h\u00fccre do\u011frudan hastal\u0131ktan etkilenen ceninlere enjekte edilecek.15 bebe\u011fe hem rahimde, hem de do\u011fumdan sonra k\u00f6k h\u00fccre tedavisi uygulanacak.15 bebe\u011fe ise tedavi do\u011fumdan sonra uygulanacak ve daha sonra rahimdeyken de k\u00f6k h\u00fccre tedavisi g\u00f6ren bebeklerle kar\u015f\u0131la\u015ft\u0131r\u0131lacaklar.Karolinska Enstit\u00fcs\u00fc&#8217;nden Dr. Cecilia Gotherstrom da yapt\u0131\u011f\u0131 a\u00e7\u0131klamada &#8220;Kemiklerin k\u0131r\u0131lmas\u0131ndaki s\u0131kl\u0131\u011f\u0131 azaltabilir, kemikleri ve b\u00fcy\u00fcmeyi g\u00fc\u00e7lendirebilirsek b\u00fcy\u00fck bir etkisi olacak&#8221; dedi.K\u00f6k h\u00fccre tedavisi \u00e7ocuklarda hastal\u0131\u011f\u0131n etkilerini hafifletiyor. Tedaviye daha da \u00f6nce, kemikler geli\u015firken ve h\u0131zla b\u00fcy\u00fcrken ba\u015flamak daha etkili olma potansiyeli ta\u015f\u0131yor.\u0130lk klinik denemeRahimde k\u00f6k h\u00fccre tedavisi daha \u00f6nce iki vaka \u00fczerinde kullan\u0131ld\u0131. Ancak klinik deneme olmaks\u0131z\u0131n tedavinin ne \u00f6l\u00e7\u00fcde etkili oldu\u011funu \u00f6l\u00e7mek imk\u00e2ns\u0131z.Dr. Gotherstrom tedavinin bir g\u00fcn Duchenne Kas Distropisi ve di\u011fer kemik hastal\u0131klar\u0131nda da i\u015fe yarayabilece\u011fini s\u00f6yledi.Tedavi ilk olarak gebeli\u011fin 20 ila 34&#8217;\u00fcnc\u00fc haftas\u0131nda, k\u00f6k h\u00fccrenin bebe\u011fin spermi ya da yumurtal\u0131klar\u0131n\u0131n bir par\u00e7as\u0131 olmas\u0131n\u0131 \u00f6nlemek i\u00e7in, erbezleri ya da yumurtal\u0131klar\u0131n olu\u015fmas\u0131ndan sonra uygulanacak.V\u00fccudun organ naklinde g\u00f6r\u00fclebilece\u011fi gibi k\u00f6k h\u00fccreyi reddetmesi olas\u0131l\u0131\u011f\u0131n\u0131n da d\u00fc\u015f\u00fck oldu\u011fu kaydediliyor.Ayr\u0131ca bu \u00e7al\u0131\u015fma, di\u011fer bir \u00e7ok olas\u0131 hastal\u0131\u011f\u0131n, bebek hen\u00fcz do\u011fmadan tedavi edilebilece\u011finin de bir g\u00f6stergesi olmu\u015f olacak.\u0130lk Yay\u0131n Tarihi: 5 May\u0131s 2017 @ 02:20"},{"@context":"http:\/\/schema.org\/","@type":"BreadcrumbList","itemListElement":[{"@type":"ListItem","position":1,"item":{"@id":"https:\/\/sevgilibebek.com\/#breadcrumbitem","name":"Sevgili Bebek"}},{"@type":"ListItem","position":2,"item":{"@id":"https:\/\/sevgilibebek.com\/anne-karninda-kok-hucre-tedavisi-mumkun\/#breadcrumbitem","name":"Anne Karn\u0131nda K\u00f6k H\u00fccre Tedavisi M\u00fcmk\u00fcn"}}]}]